Polynucleotide Advice & Information

Plinest is an injectable product designed to improve skin health and appearance. It contains polynucleotides, derived from trout sperm. Polynucleotides are clinically proven to stimulate the biological regeneration of the skin’s architecture, including collagen, elastin, hyaluronic acid, blood vessels, pigment and supporting fat cells.

Treatment with Plinest is indicated to improve skins texture, improve discolouration, skin tone, fine lines, hydration and radiance. Plinest can also be used to improve the appearance of scars.

The treatment involves multiple injections with a fine needle, of micro-doses into the surface of the skin. A blunt-tipped cannula may also be used subject to the treat treated and the preference discussed at your consultation. 

3 to 4 treatments, three weeks apart are required to achieve optimum results and optimal longevity.

To maintain results, further treatments are recommended every six months. There are alternatives to this procedure available, including the acceptance of my present condition.

EXPECTED OUTCOME

The treatment is expected to improve the skins, appearance and quality, it is often the case that some improvement can be seen within four weeks, with a continued improvement over 6 to 12 weeks. Outcomes are dependent on biological responses and subject lifestyle factors which will vary between individuals.

Whilst you may have been advised as to a probable result, they should not be interpreted as a guarantee.

COMMON SIDE EFFECTS ASSOCIATED WITH THE INJECTION

• Pain of stinging sensation when the injection is performed
• Localised swelling, redness and or tenderness which can take up to 72 hours to settle
• The injected product will be visible as small bumps in the skin temporarily, usually settling within 12 to 72 hours. You may be able to fill bumps in the skin for a few days.
• Bleeding at the sites of injection which may leave a pink prick mark
• Itching all a sensation of heat

Comment side effects are described as mild to moderate, all expected to be temporary and generally settle within a few hours or days. Bruising can take up two weeks to resolve.

Due to the reactions described above, this may inhibit your confidence to attend work or other social events. Please allow time for the common reactions such as bruising bumps, pinprick marks and swelling to settle.

UNCOMMON SIDE EFFECTS ASSOCIATED WITH INJECTIONS

• Infection
• Inflammation
• Skin discolouration
• Allergic or sensitivity reaction * maybe associated with topical antiseptics or anaesthetics. 
• Persistent lumps, nodules are papules *reported with similar products

Although these complications are uncommon, they do sometimes occur and every individuals experiences vary.

If you experience or suffer any adverse reactions that are not expected then you must contact the clinic as an appointment will be made for you to be seen. Unfortunately the clinic cannot take responsibility for complications which are results that have not been reported, assessed, documented and managed in a timely fashion.

AFTERCARE ADVICE

• Iced gauze to the treated area
• Avoid physical strain or sports for 24 hours post treatment
• No further cosmetic therapies for a 7 to 14 days pre or post treatment
• Botox should be administered 14 days prior if required
• Avoid the use of sauna, steam rooms, icy temperature or UV radiation for 2 weeks post treatment.
• Stay hydrated, 1-2 litres of water as a minimum per day
• Do not rub, massage, apply make-up to the treated area(s) for at least 4 hours post post procedure
• If you are due to travel, procedures should be done 14 days pre or post.

PRECAUTIONS AND CONTRAINDICATIONS

• This treatment will not be used in patients under the age of 18.
• Polynucleotides will not be administered to patients with the following:

1. ongoing herpes infection
2. Infection
3. Previous or ongoing, autoimmune disease or patients undergoing immunotherapy
4. Serious allergies or know allergic reactions
5. Allergies to any of the product, components

• The risk of bruising or bleeding, maybe increased by medications with anticoagulant effects, such as aspirin and non-steroidal anti-inflammatory drugs (e.g. Ibuprofen, Aleve, Motrin, Celebrax), hi doses of vitamin E, and certain herbs (ginkgo biloba, St John’s Wart).
• This treatment will not be used in pregnant or breastfeeding women